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It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus

The Anti-Fibrotic Potential of GLP-1 and GIP Receptor Agonists in Chronic Inflammatory Disorders: Mechanisms and Therapeutic Horizons

J Biol Chem (2003) 278:1040816.10.1074/jbc.M209655200 85 ThelinWRChenYGentzschMKredaSMSalleeJLScarlettCOet alDirect interaction with filamins modulates the stability and plasma membrane expression of CFTR

What blood alcohol concentration (BAC) levels are associated with death