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Products from unregulated online vendors are not manufactured under pharmaceutical standards, may contain incorrect concentrations or be mislabeled, have no guarantee of sterility or freedom from contamination, are often produced overseas in facilities with unknown quality controls, and carry zero accountability if something goes wrong

Clinical trial studies regarding the effect of -LA supplementation on migraine were limited, and the existing studies prescribed different therapeutic doses without examining the serum level of -LA

Liver function markers (ALT, TBIL, AST, ALB), fibrosis markers (HA, PC III, LN), and liver fibrosis grades were assessed pre-and post-treatment

In summary, after consideration of the public comment, we are finalizing our proposal without modification