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Fluoxetine and vortioxetine decrease QA levels in the frontal cortex, hippocampus, striatum, midbrain, hypothalamus, and cerebellum of Flinders Sensitive Line rats, a genetic rat model of depression [197]

Of the individuals with schizophrenia, the mean age of onset was 22.74 (SD = 9.70) years, while the mean duration of illness was 4.48 (SD = 2.67) years

Disruption of NOS1 dimerization can lead to abnormal CDK5 phosphorylation and activation, which impede synaptic plasticity and promote AD development [83, 84]