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As a complex disease involving multiple factors and genetic interactions, the etiology and pathogenesis of IBD remain unclear, but it is generally believed to be associated with environmental factors, genetic susceptibility, gut microbiota, and immune responses [260]

- Preventing cancer progression

Common plateau scenarios include: The circulation bottleneck: repair stalls because nutrient delivery is insufficient The remodeling bottleneck: pain improves but stability does not return The inflammation bottleneck: repair attempts are repeatedly interrupted by flare cycles The structure bottleneck: collagen forms but remains disorganized and weak GLOW is designed to support these simultaneously

Computed tomography involves a significant dose of radiation (approximately 10 millisieverts)