doi: 10.1016/j.ejphar.2023.175801 191
Collectively, our findings demonstrate that the GPX4 inhibition by RSL3 in PTC cells induces cell death, ferroptosis, lipid peroxidation, increased intracellular ROS burden, and significantly impairs thyroid tumor cell migration, 3D PTC spheroid fotmation and results in reduced spheroid viability in vitro
Tirzepatide has been found to improve markers of -cell function, such as increased HOMA2-B indices and reduced proinsulin levels, proinsulin/C-peptide ratios, and proinsulin/insulin ratios, indicating better insulin processing and reduced -cell stress [22,23]
Introduce fibre slowly over several weeks to minimise bloating and gas, which can be problematic alongside GLP-1-related gastrointestinal effects