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BPC-157 demonstrates effectiveness for tendon and ligament healing in preclinical animal models, though confirmed human efficacy data does not exist in published clinical trials

Variations in study design, experimental conditions, and evaluation methods often lead to inconsistent or non comparable results across studies

To further confirm this result, we treated tendon fibroblasts with BPC 157 at different concentrations (0, 0.1, 0.25 and 0.5 g/mL) for 24 h and the expression of growth hormone receptor was found to increase in a dose-dependent manner (Figure 1A,C)

However, intranasal administration is also considered an efficient route for systemic effects due to the dense vasculature of the nasal mucosa