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While the primary cause of CVS is still unknown, it is believed that genetic and environmental factors play a significant role in its development

[7] [8] If you notice persistent lumps, hardness, or skin changes at injection sites, contact your GP or diabetes nurse, as you may need to avoid that area temporarily and receive guidance on technique refinement

Specifically, this can include the big four: Nausea Diarrhea Vomiting Constipation Also relatively common are abdominal pain and dyspepsia (discomfort or pain in the upper abdomen after eating or drinking)