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Trends Endocrinol Metab (2021) 32(4):21223

Antioxidants such as Vitamins A, C, and E provide radiation protection because radiation damage mimics oxidative stress associated with active oxygen toxicity.[] Tocopherol monoglucoside, a water-soluble Vitamin E derivative, has been found to be very effective in protecting DNA after oral or intraperitoneal administration of DNA against in vitro as well as gamma radiation.[] Melatonin (N-acetyl-5-methoxytryptamine), a pineal hormone that plays a role in the regulation of the neuroendocrine axis, is a highly effective free radical scavenger and antioxidant.[] When administered to mice before exposure to radiation, melatonin offered significant radiation protection, which is assessed by the frequency of chromosomal abnormalities in bone marrow cells, spermatogonia, spermatocytes and micronuclei.[] This study was performed to evaluate oxidative status, DNA damage and histopathological changes of radiation-induced lung injury

Glutathione enhances cellular energy production by reducing oxidative stress and supporting mitochondrial function

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