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It reversed glucose dysregulation without detrimental effects on metabolically healthy animals and reduced body weight, lowered fasting blood glucose, decreased glycosylated hemoglobin (HbA1C), improved glucose tolerance, and protected pancreatic islet architecture in diabetic fatty Zucker rats 14,19,20

Currently, Medicare pays for these drugs only when prescribed for diabetes or, more recently, sleep apnea

Possible interactions include: Colchicines Heavy alcohol intake This list may not describe all possible interactions

Tirzepatide is FDA-approved for type 2 diabetese, but it is used off-label in treating obesity and weight concerns