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Maintaining adequate antioxidant capacity allows the body to adapt to physical stressors without tipping into prolonged fatigue or immune vulnerability

Preclinical Studies in Diabetic Experimental Models Concerning diabetic retinopathy, in vivo studies in diabetic rats demonstrated that long-term administration of ALA exerts inhibitory effects on the development of diabetic retinopathy through inhibition of the accumulation of oxidatively modified DNA, indicating that ALA supplementation as adjunctive therapy may help prevent vision damage in patients with diabetes [64]

Future investigations could benefit from techniques such as CUT&Tag (Cleavage Under Targets and Tagmentation) or CLIP-seq (Cross-Linking Immunoprecipitation followed by Sequencing), particularly m6A-specific variants like m6A-CUT&Tag or miCLIP/m6A-CLIP-seq