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Experimental evidence supports the functional importance of CoQ biosynthesis in ferroptosis suppression: recent unbiased screens in myeloma cells identified COQ2 as a factor promoting proliferation and suppressing lipid peroxidation, suggesting enhanced resistance to ferroptosis 35

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[DOI] [PubMed] [Google Scholar] 32.Goldberg E.L., Asher J.L., Molony R.D., Shaw A.C., Zeiss C.J., Wang C., Morozova-Roche L.A., Herzog R.I., Iwasaki A., Dixit V.D

Results suggested it may help sustain thymic activity in mature models, with tentative findings of reduced systemic inflammation, modulated cortisol patterns, and more stable metabolic parameters