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Therefore, this study aimed to compare two intranasal vitamin B12 dosage regimens (with and without loading dose) in elderly patients deficient in vitamin B12, focusing on vitamin B12 levels and three biomarkers indicative of deficiency: holotranscobalamin, methylmalonic acid, and total homocysteine

Microdosing is helpful for such patients, as it allows them to test their bodys response with smaller doses

In addition, we used protein immunoprecipitation to verify the interaction between GLP-1R and the PKA/CREB pathway

We will also follow up regularly to monitor your progress, answer questions, and adjust your plan as needed based on how you are sleeping, recovering, and feeling overall