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Leukocytes link local and systemic inflammation in ischemic cardiovascular disease: an expanded cardiovascular Continuum
Carnitine A key amino acid that facilitates the transport of fatty acids into cells to be burned as energy, enhancing fat metabolism and athletic performance
The liposome-reduced glutathione preparation described is also stable from oxidation, allowing a two year, unrefrigerated shelf-life of the product, and has specific characteristics of uptake into cell membranes that improve its therapeutic qualities for certain disease states
To break through these bottlenecks, structural modification and advanced formulation design have emerged as effective solutions: structural modification can optimize the pharmacokinetic properties of saponins, while formulation strategiesespecially nanotechnology-based drug delivery systems (e.g., poly(lactic-co-glycolic acid) nanoparticles, liposomes)can significantly improve their solubility, bioavailability, and tumor targeting, thereby reducing off-target toxicity and enhancing therapeutic efficacy
