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2), 16,17 many of these studies have focused on the relevance of glutamate, mainly in the central nervous system, describing a correlation between increased glutamate efflux and increased cancer aggressiveness and invasive capacity (and, consequently, poor prognosis)

3A), but a significant interaction between time and group was not observed

In order to determine whether the effect of GH is direct in AgRP cells (independent of action potential-mediated synaptic transmission), a new set of recordings was performed in the presence of the voltage-gated sodium channel antagonist tetrodotoxin (TTX