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Myeloid Trem2 in pro-inflammatory macrophages activates ras-related C3 botulinum toxin substrate 1 (Rac1) through the cyclooxygenase 2/prostaglandin E2 (COX2/PGE2) pathway, promoting the phagocytosis of apoptotic cells accumulated following hepatic ischemia-reperfusion injury in mice, and facilitating macrophage efferocytosis to suppress inflammation (Kwon et al., 2024

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Polar cuticular lipids of workers bind to the Si CSP1 protein, contributing to nestmate recognition, while fatty acids from decaying corpses trigger a necrophoric behavior ( Si CSP1-mediated corpse recognition could compromise nest sanitation efficiency, potentially increasing colony susceptibility to pathogens or reducing social cohesion

Ilic et al., 2009