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This gives a novel mechanism in which MT, through downregulation of TRIP13, slows down aberrant DNA repair and proliferation of cancer cells

They are generally not recommended during pregnancy or breastfeeding, for people with a known allergy to any component of the formulation, or for those with certain medical conditions

What they found: Significant improvement in sexual desire vs placebo Improvement in arousal and genital congestion No serious side effects Mild nausea in some subjects Why it matters: PT-141 (Bremelanotide) is an MC4R-selective fragment of Melanotan II optimized for sexual function