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When glutathione stores deplete, NAPQI metabolites accumulate unchecked, binding to hepatocyte proteins and triggering cell death

Safety and precautions: Because pure bacteriostatic water is hypotonic, it should not be injected alone intravenously (doing so can cause red cell hemolysis)

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By mapping the cascade from zinc imbalance to molecular dysfunction, organelle stress and disease expression, the framework provides an early overview that anchors the detailed sections that follow and highlights mechanistic points of intervention with potential relevance for future therapeutic modulation 18,19,20,21