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When the inflammatory signal of periodontitis was enhanced or prolonged, SOD2 expression was upregulated by activating the NF-B signaling pathway [64]

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In animal models, L-theanine appears to have a dose-dependent biphasic effect on NSAID-induced gastric ulcers, delaying healing at higher doses (40 mg/kg), but accelerating healing at lower doses (10 mg/kg) perhaps through the maintenance of glutathione levels thus protecting against oxidative damage (26)