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In colorectal cancer patients treated with the FOLFOX regimen (fluorouracil, calcium folinate combined with oxaliplatin), platinum residues remain detectable in dermal collagen fibers up to 60 months post-withdrawal, mediating persistent, distally distributed neuropathy via damaging cutaneous sensory nerve fibers (Cao et al

Phytother Res 25:544549 Hassan MQ, Hadi RA, Al-Rawi ZS, Padron VA, Stohs SJ (2001) The glutathione defense system in the pathogenesis of rheumatoid arthritis