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Next, CCK-8, EdU, and cell cycle assays were conducted to investigate the biological function of IGF-1 in DPCs and DSCs

In the second study, which lasted 49 days, test subjects received CJC-1295 or placebo in two or three weekly or biweekly doses

Lactate oxidase provides a direct strategy by catalyzing lactate oxidation to pyruvate and H2O2, reducing lactate levels, exacerbating tumor hypoxia and increasing oxidative stress (150)