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Increased levels of TFAs may also contribute to the pathogenesis of mental disorders as a result of altering the neuronal lipid membrane composition, leading to reduced levels of polyunsaturated fatty acid content, reduced membrane fluidity, and impaired neurotransmission (28, 30, 31)

Diabetes alters the expression profiles of numerous non-coding RNAs in sperm, especially miRNAs, which may influence spermatogenesis and fertility [199]