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Injectable semaglutide (Ozempic, Wegovy) did not show a clinically significant effect on oral contraceptives specifically in FDA trials, but the label still recommends monitoring all oral medications, given the same underlying mechanism

No difference was observed between the two groups in the normal intake of diet and drinking consumed per day (Fig

Therefore, they shouldnt be taken together without medical advice

Since many of the adverse events and discontinuations occurred before maintenance doses were achieved, Nauck and Horowitz suggest that the priority may be to find ways to improve tolerability of oral GLP-1 RAs, including by exploring dose-escalation regimens