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Importantly, although MenSCs exhibit strong migratory capacity due to high CXCR4 expression (Luz-Crawford et al., 2016), dysfunctional fibroblasts in diabetic wounds often fail to produce stromal cell-derived factor-1, thereby compromising MenSC homing efficiency (Mirzadegan et al., 2022

Evidencia clnica Actualmente tenemos evidencia muy limitada que respalde el uso de medicamentos GLP-1 o duales GIP/GLP-1 en el tratamiento de adultos con diabetes tipo 1