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One study found that taking 500 to 1000 mg of vitamin C daily for 13 weeks increased white blood cell glutathione by 18%

CrossRef Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes Federica Zatterale, Michele Longo, Jamal Naderi, Gregory Alexander Raciti, Antonella Desiderio, Claudia Miele, Francesco Beguinot Frontiers in Physiology.2020;[Epub] CrossRef Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases

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Many of these side effects will resolve within a couple of days and can be diminished with over-the-counter pain meds