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Moreover, the upregulation of the HIF-1 signaling pathway and the downregulation of the Hippo pathway observed in the current transcriptomic and RT-PCR analyses should be interpreted as preliminary and descriptive findings

Interestingly, when cecal contents from atherosclerosis-prone C57BL apo E / mice were transplanted into germ-free recipient mice fed a choline-supplemented chow diet, the recipient mice developed significantly larger aortic lesions after 16 weeks compared to germ-free recipients that received cecal contents from atherosclerosis-resistant NZW apo E / mice [153]

95% CI -0.7 to 1.5 per 1000 person-years

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