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An independent licensee of the Blue Cross Blue Shield Association, Highmark Inc., together with its Blue-branded affiliates, collectively comprise the fifth largest overall Blue Cross Blue Shield-affiliated organization in the country with more than 7 million members in Pennsylvania, Delaware, West Virginia and western and northeastern New York

doi: 10.1007/s00259-019-04543-w 73 MilanGReemaGSimoneKKevinDSJamesJHIngoKMet al

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[29] By preventing PCSK9-mediated degradation of LDL receptors, these agents preserve receptor recycling, lowering LDL-C by roughly 5060% with corresponding reductions in ApoB