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Description

10.1016/0006-8993(89)90007-3 Brain Res

il 18 Mag

Synapsin-Cre + male mice were mated to Gipr fl/fl female mice (previously described 17 ) to generate mice with heterozygous floxed Gipr gene with or without the synapsin-Cre transgene

In high fat diet (HFD) and streptozotocin (STZ)-induced type 2 diabetic mice model and HK-2 cells, after treatment with metformin (200 mg/kg/d) for 24 weeks, some indicators of mitophagy (LC3II, Pink1, Parkin, Atg5) were examined