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While tirzepatide's primary therapeutic targets are metabolic disorders, emerging research has begun exploring potential secondary effects on inflammatory pathways and immune function

To improve transparency, we followed a PRISMA-inspired screening logic appropriate for a narrative/scoping review: records identified across databases were de-duplicated, screened by title/abstract, and assessed in full text for relevance to cardio-renal outcomes (albuminuria, eGFR trajectory) and the personalized medicine framework

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A MOF occurred in 1.8% (n = 286) and 1.7% (n = 274) of GLP-1 RA users and DPP-4i users, respectively