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GLP-1 receptors, which are expressed in the central nervous system (CNS) in addition to peripheral tissues, are limited to neurons in the caudal nucleus of the solitary tract (NTS) and the ventrolateral medulla in the brainstem and hypothalamus (1517)

In some patients, anatomical changes such as sleeve dilation, pouch enlargement, or a dilated gastrojejunal anastomosis may contribute to difficulty with portion control

In some cases, internal hemorrhoids can protrude outside the anus, a condition known as prolapsed hemorrhoids, which may require medical intervention for relief

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