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Kumar et al , 2011), GSH does serve an essential role in iron metabolism by cooperating with monothiol glutaredoxins in the assembly of ironsulphur clusters (Lee et al , 2001

NAC, N -acetylcysteine

They seem to be well tolerated in patients with mild and moderate liver function impairment, though they should be cautiously administered in patients with advanced liver disease.77,78 SGLT2 inhibitors Selective renal sodium glucose co-transporter 2 (SGLT2) inhibitors improve glycemic control in an insulin-independent fashion through inhibition of glucose reuptake in the kidney.79 The most used drugs from this group are: dapagliflozin, canaglifozin and empaglifozin

In fact, a few of these patients were diagnosed with severe and life-threatening gastrointestinal complications that required surgery and other kinds of emergency medical treatment