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In the full episode, we cover: -The core arguments against seed oils: the four main claims underlying the idea that seed oils are uniquely harmful, and how well they hold up once major confounders are addressed -The historical trials that shaped the debate: the Minnesota Coronary Experiment, Sydney Diet Heart Study, Rose Corn Oil trial, and later studies replacing saturated fat with polyunsaturated fat -Mechanisms and causality: LDL cholesterol, oxidized LDL, linoleic acid (omega-6), inflammation, -Mendelian randomization, and why lifetime LDL exposure matters more than per-particle oxidation risk -Practical takeaways: industrial processing concerns, cooking oils, real-world dietary fat choices, and how to prioritize nutrition relative to calories, activity, and overall lifestyle factors Listen (Ep