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Fascicular structure of the vagus nerve trunk The arrangement of fibers in the nerve plays an important role in neuromodulation therapies, as the activation or block of nerve fibers by electrical stimulation using an implanted electrode depends heavily on the distance between the electrode and the fibers: the shorter the distance, the smaller the stimulus intensity required to engage fibers (Grill and Mortimer 1997)

e-pub ahead of print 2007/03/21

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Clinical context and symptom severity should guide decisions