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doi: 10.3389/ti.2022.10810 16 HillCJCourtneyAECardwellCRMaxwellAPLucarelliGVerouxMet al

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In addition to effects on NO, GLP-1 RAs may impact other vasoactive mediators such as the renin-angiotensin-aldosterone system (RAAS)

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The studys inclusion of a diverse participant pool and strict randomization protocols provided robust and credible data on the benefits and risks of cagrilintide and semaglutide combination therapy

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The disease constitutes 5-10% of diabetes, and the disease is rising as a significant clinical and public health burden globally ( Unlike type 2 diabetes mellitus, for which many drug choices are available, the only available therapy for type 1 diabetes is insulin (Sodium Glucose cotransporters inhibitors are used as adjuvant therapy for uncontrolled T1DM and a body mass index (BMI) of 27 kg/m 2 )

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