FIGURE 1 In vitiligo patients, high IFN- expression has been implicated in an aggressive and permanent IS response (IFN- CXCL10 (C-X-C Motif Chemokine Ligand 10) CD8 + T cells) (Xie et al., 2016) targeting the population of epithelial cells throughout the body causing visual (Agarwala and Malkud, 2020), hearing (Ma et al., 2021) and vascular dysfunction (Azzazi et al., 2021)
NA, MA, and FN participated in constructive outline, discussions, and editing
We encourage you to consider your lifestyle and how your body responds to supplementation
If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy