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Additionally, GLP-1 medications are not recommended during pregnancy, and for semaglutide specifically, treatment should be discontinued at least 2 months before a planned pregnancy

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Preclinical data suggests that triple agonism may shift the ratio of fat-to-lean mass loss in a more favorable direction

[2] If you're planning pregnancy, contact your provider well in advance, as these medications should be discontinued (semaglutide at least 2 months before planned conception) due to limited safety data in pregnancy