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Published research has described gastrointestinal adverse events as dose-related
EMERGING RISK SIGNALS A recent analysis published in The British Medical Journal (BMJ) Medicine has found that patients who discontinue GLP-1 therapies may face increased cardiovascular risks
It requires careful management to prevent complications and maintain a good quality of life
GLP-1RAs improve hyperglycemia by enhancing insulin secretion through increases in -cell cytoplasmic cyclic adenosine monophosphate [53], which activates protein kinase A (PKA) and, thus, increases in intracellular calcium and triggers insulin exocytosis in a glucose-dependent manner [54]
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