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Given the known off-target effects of APR-246, we investigated whether the mutant-specific effects observed in OVCAR5 cells were attributable to intrinsic differences in redox homeostasis among the parental p53-null cell lines
Towards precision medicine in heart failure
Fasting blood glucose monitoring included measurements at 7 and 14 days after the last STZ injection
Interstitial Cystitis Study (2024) Study design : Pilot study Participants : 12 women (ages 39-76) with moderate to severe interstitial cystitis who had failed pentosan polysulfate treatment Intervention : Intravesical (bladder) injection of 10mg BPC-157 Follow-up : 6 weeks Results : 10 of 12 patients reported complete resolution of symptoms
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