Both routes share the following common outcomes: pain at the injection site, hypertension development, arteriovenous fistulae thrombosis, hyperkalemia, iron store depletion, flu-like symptoms, prolonged dialysis, and, infrequently, pure red cell aplasia (PRCA) and seizures
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Katel A, Aryal M, Neupane A, Gosain R, Pathak R, Bhandari Y, Kouides P (2021) Efficacy and safety of direct oral anticoagulants in venous thromboembolism compared to traditional anticoagulants in morbidly obese patients: a systematic review and meta-analysis
The holo-TC test measures precisely this important fraction, which makes up only about 10-20% of total vitamin B12