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as a key regulator of mitochondrial biogenesis, PGC1 enhances mitochondrial function in myoblasts, supplies sufficient energy for differentiation, and regulates the transcription of myogenic genes to accelerate myotube maturation

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Additionally, future studies should investigate the long-term effects of microbiome-based interventions and explore the potential of personalized medicine approaches tailored to individual patients gut microbial profiles (Cunningham et al., 2021)