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Levocarnitine was not bound to plasma protein or albumin when tested at any concentration or with any species including the human.9 In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

Nausea, vomiting, and diarrhea are common, especially during dose escalation

Most side effects are mild and gastrointestinal in naturesuch as nausea, vomiting, or diarrheaand tend to diminish over time with proper management