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Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 * C, cloned from a glioblastoma multiforme cell line
The formation of chromatin loops before the recruitment of the activators facilitates the communication between the promoters and enhancers
Elevated IGF-1 activity has been associated with tumor cell proliferation and, epidemiologically, with certain cancer risks, which is why IGF-1R has been pursued as a target for inhibition in oncology
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