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Moreover, overproduction of ROS has an impact to enhance the cancer cell proliferation, migration, metastasis, invasiveness and poor prognosis through many cellular mechanisms like matrix degradation, cell-cell contact, cell remodelling, as well as regulation of gene expression [54]

In rat models, GHK-Cu's neuroprotective effects were evident through improved neurological deficits, reduced brain swelling, and inhibition of neuron death

Finally, dietary glutamine increased the number of IgA-secreting B cells in the small intestine of young mice (156) and enhanced intestinal levels of IgA in various weaning animals (157161)

Sham-operated rats underwent the same surgical procedure except for the MCA occlusion