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"These drugs reduce your appetite, but if youre skipping meals or eating nutritionally poor foods, you risk low energy, nutrient deficiencies, muscle and bone loss, and even mental health issues

Earlier Phase 2 monotherapy work also studied higher weekly doses up to 4.5 mg, but the cagrilintide-only schedule above matches the 2.4 mg weekly target shown throughout this page

doi: 10.1186/s12974-023-02879-7 255 LiuYHongTLvMGuoXZhangPYanAet al

Neurotoxic striatal dopamine depletion: VMAT2 reversal and methamphetamine-generated oxidative stress damage dopaminergic terminals in the frontostriatal system, producing persistent deficits in memory, attention, and executive function that outlast acute withdrawal by months