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Although the enrichment of L-cells by pharmacological agents can be a novel approach for improving insulin secretion, glucose tolerance and the treatment of T2DM, more research for the specific differentiation of L-cells and the translation of in vitro and animal data to humans, are needed for the success of this approach

Spontaneous alternation was considered a trio sequence of entries into three different arms (e.g., A-B-C, B-C-A) as mice with strong working memories are more likely to enter an arm least visited rather than one visited directly prior

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