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The association remained significant after matching for key risk factors, such as age, race, ethnicity, BMI, breast density, and diabetes status, suggesting the findings were not solely due to differences between groups

Reaching clinical steady-state typically requires 45 weeks, during which tissue saturation gradually increases and metabolic effects become more pronounced

Zhang X, Liu J, Bai C, Fan Y, Song H, Huang Z, et al

KEGG analysis revealed the upregulation of adaptive and metabolic pathways, such as circadian rhythm regulation, amino acid metabolism, and notably, the HIF-1 signaling pathway (Figures 6d,e)