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Salter AM, Fisher SC, Brindley DN: Binding of low-density lipoprotein to monolayer cultures of rat hepatocytes is increased by insulin and decreased by dexamethasone

On the other hand, the American Diabetes Association (ADA) has recommended this combination for its beneficial effect on preserving kidney function and also improving cardiovascular indexes [48]

The aim is not to discourage appropriate treatment, but to make sure warning symptoms are recognised early

There are documented case reports of extreme appetite suppression and psychiatric complications requiring GLP-1 discontinuation in people with restrictive eating patterns ( Leziak et al., J Psychiatric Research, 2026 )