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One of the major limitations of this study, however, there is lack of evidence of direct linkage of the proposed biomarkers with complications of diabetes (e.g., longitudinal follow-up study), which is important evidence base towards clinical utility of the proposed biomarkers

In the preparation of the L-carnitine-contained wheat flour-dough particles, L-carnitine was first dissolved in pure water, and the carnitine solution was mixed with given amount of wheat flour to make wet dough

Long-term human safety data remains limited due to the compounds regulatory status

A 2024 study published in Gut Microbes demonstrated that oral glutathione at 1000mg daily shifted microbiome composition away from butyrate-producing species like Faecalibacterium prausnitzii and Roseburia species