Selain sebagai antioksidan, glutathione juga terlibat dalam berbagai proses detoksifikasi tubuh
Specific polymorphisms, such as CLOCK rs11133373, PER3 VNTR, and MTNR1A rs2119882, have been associated with differential susceptibility to circadian misalignment and cancer risk 270 , hence they can be used for risk stratification purposes
Therefore, researchers are now concentrating on innovative studies exploring the molecular mechanisms of oxidative stress to develop causative antioxidant therapy
Microbes can directly or indirectly regulate mitochondrial function through metabolites, such as short chain fatty acids (SCFAs), H 2 S, and NO, affect mitochondria-related energy metabolism, regulate the production of ROS, and regulate the immunity of mitochondria and even the whole body [15,16]