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BBS can be diagnosed based on clinical features (e.g., retinal dystrophy, obesity, postaxial polydactyly) using the Beales diagnostic criteria

Here's what it is, how it works, and why it matters specifically for Pakistani skin

Rather than replicating the full TB4 protein, TB-500 is based on the short actin-binding fragment responsible for much of TB4s cell-migration activity, which makes it more practical to synthesise for research use

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