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Between 2 and 12% of patients receiving high-dose MTX therapy may get acute kidney injury, mostly as a result of crystal nephropathy caused by MTX and its metabolite, 7-OH-MTX

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Administered as a once-a-week injection, each of these drugs regulates hunger so we eat fewer calories, slows stomach emptying so we stay fuller for longer, and turns off the messages in our head that make us seek out certain foods

Choosing Between Them for Research There cannot be said to be one compound that is better than the other the appropriate compound will always depend on the specific research being carried out